NIEHS/NTP Workshop: Role of Environmental Chemicals in the Development of Diabetes and Obesity

NIEHS/NTP Workshop:y: "There has been increasing interest in the concept that environmental chemicals may be contributing factors to the epidemics of diabetes and obesity. The National Toxicology Program (NTP) is holding a workshop to evaluate the science associating exposure to certain chemicals or chemical classes with the development of diabetes and obesity in humans. Participants at the workshop will:"

Evaluate strength/weaknesses, consistency, and biological plausibility of findings reported in humans and experimental animals for certain environmental chemicals including arsenic and cadmium, PCBs, DDT/DDE, other organohalogens, bisphenol A, phthalates, and organotins.

Identify the most useful and relevant endpoints in experimental animals and in vitro models.

Identify relevant pathways and biological targets for assays for the Toxicology Testing in the 21st Century high throughput screening initiative ("Tox21").

Identify data gaps and areas for future evaluation/research.